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Successful Identification of Cardiac Troponin Calcium Sensitizers Using a Combination of Virtual Screening and ROC Analysis of Known Troponin C Binders.
Aprahamian, Melanie L; Tikunova, Svetlana B; Price, Morgan V; Cuesta, Andres F; Davis, Jonathan P; Lindert, Steffen.
Afiliação
  • Aprahamian ML; Department of Chemistry and Biochemistry, Ohio State University , Columbus, Ohio 43210, United States.
  • Tikunova SB; Davis Heart and Lung Research Institute and Department of Physiology and Cell Biology, Ohio State University , Columbus, Ohio 43210, United States.
  • Price MV; Davis Heart and Lung Research Institute and Department of Physiology and Cell Biology, Ohio State University , Columbus, Ohio 43210, United States.
  • Cuesta AF; Davis Heart and Lung Research Institute and Department of Physiology and Cell Biology, Ohio State University , Columbus, Ohio 43210, United States.
  • Davis JP; Davis Heart and Lung Research Institute and Department of Physiology and Cell Biology, Ohio State University , Columbus, Ohio 43210, United States.
  • Lindert S; Department of Chemistry and Biochemistry, Ohio State University , Columbus, Ohio 43210, United States.
J Chem Inf Model ; 57(12): 3056-3069, 2017 12 26.
Article em En | MEDLINE | ID: mdl-29144742

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Cálcio / Cromanos / Troponina C Tipo de estudo: Diagnostic_studies / Guideline / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Cálcio / Cromanos / Troponina C Tipo de estudo: Diagnostic_studies / Guideline / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article