The VEGF paradox: Does diabetic retinopathy protect from age related macular degeneration?
Med Hypotheses
; 109: 156-161, 2017 Nov.
Article
em En
| MEDLINE
| ID: mdl-29150277
ABSTRACT
Age-related macular disease (AMD) and diabetic retinopathy (DR) are prevalent diseases. Vascular endothelial growth factor (VEGF) related retinal neovascularization is a common feature in both. Consequently, both pathologies are treated with anti-VEGF therapy. We have previously reported a lower incidence of AMD in patients with DR compared to controls. The present study hypothesizes that DR in stages in which the concentration of intravitreal VEGF is increased, might have a protective role for both the onset and development of AMD.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Oxigênio
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Neovascularização Retiniana
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Neovascularização de Coroide
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Fator A de Crescimento do Endotélio Vascular
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Retinopatia Diabética
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Degeneração Macular
Tipo de estudo:
Prognostic_studies
Limite:
Aged
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Humans
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Middle aged
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article