Growth Hormone as Biomarker in Heart Failure.
Heart Fail Clin
; 14(1): 65-74, 2018 Jan.
Article
em En
| MEDLINE
| ID: mdl-29153202
ABSTRACT
The impairment of growth hormone (GH)/insulin growth factor-1(IGF-1) plays a crucial role in chronic heart failure (CHF). Several studies have shown that patients affected by this condition display a more aggressive disease, with impaired functional capacity and poor outcomes. Interestingly, GH replacement therapy represents a possible future therapeutic option in CHF. In this review, the authors focus on the assessment of the main abnormalities in GH/IGF-1 axis in CHF, the underlying molecular background, and their impact on disease progression and outcomes.
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Base de dados:
MEDLINE
Assunto principal:
Hormônio do Crescimento Humano
Limite:
Humans
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article