Dietary total, animal, vegetable calcium and type 2 diabetes incidence among Korean adults: The Korean Multi-Rural Communities Cohort (MRCohort).
Nutr Metab Cardiovasc Dis
; 27(12): 1152-1164, 2017 Dec.
Article
em En
| MEDLINE
| ID: mdl-29167059
ABSTRACT
BACKGROUND AND AIMS:
Although a possible mechanism for developing type 2 diabetes in relation to calcium intake has been suggested, there is currently little epidemiological evidence on the association between dietary calcium and type 2 diabetes (T2D). This study aimed to evaluate the prospective association between dietary calcium and T2D incidence among adults 40 years of age or over, from the Multi-rural Communities Cohort (MRCohort), South Korea. METHODS ANDRESULTS:
In total, 8313 participants (3033 men and 5280 women) who did not have diabetes at baseline were recruited between 2005 and 2013. The incidence rate ratio (IRR) was estimated using a modified Poisson regression model with a robust error estimator. During follow-up (31,570 person-years), 322 T2D cases were newly diagnosed. Dietary calcium (total and vegetable calcium) were inversely associated with the risk of T2D incidence among women (IRRâ¯=â¯0.61, 95% CIâ¯=â¯0.43-0.86, P for trendâ¯=â¯0.007 in third tertile of baseline total calcium intake comparing to the first tertile; IRRâ¯=â¯0.57, 95% CIâ¯=â¯0.39-0.84, P for trendâ¯=â¯0.006 for baseline vegetable calcium intake), not for men. The tendency of those inverse associations remained in both the normal fasting blood glucose group and the impaired fasting blood glucose group and were independent of obesity, smoking, and magnesium intake.CONCLUSIONS:
Total and vegetable calcium may be inversely associated with T2D incidence among women, regardless of impaired fasting blood glucose group or normal group. The associations may be potentially dose-responsive. Moderate dietary calcium may be related to lower risk of T2D incidence comparing to low intake group among women.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Verduras
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Cálcio da Dieta
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Saúde da População Rural
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Diabetes Mellitus Tipo 2
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Comportamento Alimentar
Tipo de estudo:
Clinical_trials
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Diagnostic_studies
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Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article