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A new steroidal saponin from Polygonatum sibiricum.
Zhang, Hong-Yang; Hu, Wei-Cheng; Ma, Guo-Xu; Zhu, Nai-Liang; Sun, Xiao-Bo; Wu, Hai-Feng; Xu, Xu-Dong.
Afiliação
  • Zhang HY; a Center of Research and Development on Life Sciences and Environment Sciences , Harbin University of Commerce , Harbin 150076 , China.
  • Hu WC; b Key Laboratory of Bioactive Substance and Resource Utilization of Chinese Herbal Medicine, Ministry of Education , Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100193 , China.
  • Ma GX; c Jiangsu Collaborative Innovation Center of Regional Modern Agriculture & Environmental Protection , Haiyin Normal University , Huaian 223300 , China.
  • Zhu NL; d Jiangsu Key Laboratory for Eco-Agricultural Biotechnology around Hongze Lake , Haiyin Normal University , Huaian 223300 , China.
  • Sun XB; b Key Laboratory of Bioactive Substance and Resource Utilization of Chinese Herbal Medicine, Ministry of Education , Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100193 , China.
  • Wu HF; b Key Laboratory of Bioactive Substance and Resource Utilization of Chinese Herbal Medicine, Ministry of Education , Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100193 , China.
  • Xu XD; b Key Laboratory of Bioactive Substance and Resource Utilization of Chinese Herbal Medicine, Ministry of Education , Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100193 , China.
J Asian Nat Prod Res ; 20(6): 586-592, 2018 Jun.
Article em En | MEDLINE | ID: mdl-29168389
ABSTRACT
A new furostan type steroidal saponin, kingianoside Z (1), along with four known compounds (2-5), was isolated from the ethanolic extract of Polygonatum sibiricum Delar. ex Redoute. Their structures were determined by spectroscopical method and by comparison with previously reported spectroscopic data. Compounds 3-5 showed significant cytotoxicity against HepG2 cell lines with IC50 values of 14.2, 12.1 and 8.5 µM, respectively.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polygonatum / Antineoplásicos Fitogênicos Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polygonatum / Antineoplásicos Fitogênicos Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article