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Synthetic Lethality of PARP Inhibitors in Combination with MYC Blockade Is Independent of BRCA Status in Triple-Negative Breast Cancer.
Carey, Jason P W; Karakas, Cansu; Bui, Tuyen; Chen, Xian; Vijayaraghavan, Smruthi; Zhao, Yang; Wang, Jing; Mikule, Keith; Litton, Jennifer K; Hunt, Kelly K; Keyomarsi, Khandan.
Afiliação
  • Carey JPW; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. kkeyomar@mdanderson.org jpcarey@mdanderson.org.
  • Karakas C; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Bui T; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Chen X; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Vijayaraghavan S; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Zhao Y; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Wang J; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Mikule K; Tesaro Biopharmaceuticals, Waltham, Massacheusetts.
  • Litton JK; Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Hunt KK; Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Keyomarsi K; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. kkeyomar@mdanderson.org jpcarey@mdanderson.org.
Cancer Res ; 78(3): 742-757, 2018 02 01.
Article em En | MEDLINE | ID: mdl-29180466
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Piridínio / Proteínas Proto-Oncogênicas c-myc / Resistencia a Medicamentos Antineoplásicos / Compostos Bicíclicos Heterocíclicos com Pontes / Proteína BRCA1 / Proteína BRCA2 / Neoplasias de Mama Triplo Negativas / Inibidores de Poli(ADP-Ribose) Polimerases / Mutações Sintéticas Letais Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Piridínio / Proteínas Proto-Oncogênicas c-myc / Resistencia a Medicamentos Antineoplásicos / Compostos Bicíclicos Heterocíclicos com Pontes / Proteína BRCA1 / Proteína BRCA2 / Neoplasias de Mama Triplo Negativas / Inibidores de Poli(ADP-Ribose) Polimerases / Mutações Sintéticas Letais Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article