Fungal 7-epi-10-deacetyltaxol produced by an endophytic Pestalotiopsis microspora induces apoptosis in human hepatocellular carcinoma cell line (HepG2).

Subban, Kamalraj; Singh, Satpal; Subramani, Ramesh; Johnpaul, Muthumary; Chelliah, Jayabaskaran

Subban, Kamalraj; Singh, Satpal; Subramani, Ramesh; Johnpaul, Muthumary; Chelliah, Jayabaskaran.

Afiliação

Subban K; Department of Biochemistry, Indian Institute of Science, Bangalore, Karnataka, 560012, India.
Singh S; Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai, Tamil Nadu, India.
Subramani R; Department of Biochemistry, Indian Institute of Science, Bangalore, Karnataka, 560012, India.
Johnpaul M; Department of Biology, College of Engineering, Science & Technology, Fiji National University, Natabua Campus, Lautoka, Fiji Islands.
Chelliah J; Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai, Tamil Nadu, India.

BMC Complement Altern Med ; 17(1): 504, 2017 Nov 28.

Article em En | MEDLINE | ID: mdl-29183320

Assuntos

Antineoplásicos/farmacologia; Apoptose/efeitos dos fármacos; Endófitos/química; Taxoides/farmacologia; Xylariales/química; Antineoplásicos/química; Carcinoma Hepatocelular; Ciclo Celular/efeitos dos fármacos; Sobrevivência Celular/efeitos dos fármacos; Células Hep G2; Humanos; Neoplasias Hepáticas; Espécies Reativas de Oxigênio/metabolismo; Taxoides/química

Palavras-chave

7-epi-10-deacetyltaxol (EDT); Apoptosis; Endophyte; G2/M arrest; Pestalotiopsis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Xylariales / Apoptose / Taxoides / Endófitos / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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