Novel transcriptional networks regulated by CLOCK in human neurons.

Fontenot, Miles R; Berto, Stefano; Liu, Yuxiang; Werthmann, Gordon; Douglas, Connor; Usui, Noriyoshi; Gleason, Kelly; Tamminga, Carol A; Takahashi, Joseph S; Konopka, Genevieve

Fontenot, Miles R; Berto, Stefano; Liu, Yuxiang; Werthmann, Gordon; Douglas, Connor; Usui, Noriyoshi; Gleason, Kelly; Tamminga, Carol A; Takahashi, Joseph S; Konopka, Genevieve.

Afiliação

Fontenot MR; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Berto S; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Liu Y; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Werthmann G; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Douglas C; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Usui N; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Gleason K; Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Tamminga CA; Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Takahashi JS; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Konopka G; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

Genes Dev ; 31(21): 2121-2135, 2017 11 01.

Article em En | MEDLINE | ID: mdl-29196536

Assuntos

Proteínas CLOCK/genética; Proteínas CLOCK/metabolismo; Regulação da Expressão Gênica no Desenvolvimento/genética; Redes Reguladoras de Genes/genética; Neurônios/fisiologia; Linhagem Celular; Movimento Celular/genética; Epigênese Genética/genética; Técnicas de Silenciamento de Genes; Humanos; Neocórtex/metabolismo; Transtornos do Neurodesenvolvimento/genética; Neurônios/citologia

Palavras-chave

circadian rhythms; evolution; human brain; neurogenomics; neuronal migration

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação da Expressão Gênica no Desenvolvimento / Redes Reguladoras de Genes / Proteínas CLOCK / Neurônios Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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