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TRIM28 and Interacting KRAB-ZNFs Control Self-Renewal of Human Pluripotent Stem Cells through Epigenetic Repression of Pro-differentiation Genes.
Oleksiewicz, Urszula; Gladych, Marta; Raman, Ayush T; Heyn, Holger; Mereu, Elisabetta; Chlebanowska, Paula; Andrzejewska, Anastazja; Sozanska, Barbara; Samant, Neha; Fak, Katarzyna; Auguscik, Paulina; Kosinski, Marcin; Wróblewska, Joanna P; Tomczak, Katarzyna; Kulcenty, Katarzyna; Ploski, Rafal; Biecek, Przemyslaw; Esteller, Manel; Shah, Parantu K; Rai, Kunal; Wiznerowicz, Maciej.
Afiliação
  • Oleksiewicz U; Laboratory for Gene Therapy, Department of Cancer Immunology, Poznan University of Medical Sciences, 60-806 Poznan, Poland; Laboratory for Gene Therapy, Department of Diagnostics and Cancer Immunology, Greater Poland Cancer Centre, 61-866 Poznan, Poland.
  • Gladych M; Laboratory for Gene Therapy, Department of Cancer Immunology, Poznan University of Medical Sciences, 60-806 Poznan, Poland; Laboratory for Gene Therapy, Department of Diagnostics and Cancer Immunology, Greater Poland Cancer Centre, 61-866 Poznan, Poland.
  • Raman AT; Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, TX 77030, USA; Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.
  • Heyn H; Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona 08908, Catalonia, Spain; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona 08036, Spain; Universitat Pom
  • Mereu E; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona 08036, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain.
  • Chlebanowska P; Laboratory for Gene Therapy, Department of Diagnostics and Cancer Immunology, Greater Poland Cancer Centre, 61-866 Poznan, Poland; University of Life Sciences, 60-637 Poznan, Poland.
  • Andrzejewska A; Laboratory for Gene Therapy, Department of Diagnostics and Cancer Immunology, Greater Poland Cancer Centre, 61-866 Poznan, Poland; Adam Mickiewicz University, Biology Department, 61-614 Poznan, Poland.
  • Sozanska B; Faculty of Mathematics and Information Science, Warsaw University of Technology, 00-602 Warsaw, Poland.
  • Samant N; Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.
  • Fak K; Faculty of Mathematics and Information Science, Warsaw University of Technology, 00-602 Warsaw, Poland.
  • Auguscik P; Faculty of Mathematics and Information Science, Warsaw University of Technology, 00-602 Warsaw, Poland.
  • Kosinski M; Faculty of Mathematics and Information Science, Warsaw University of Technology, 00-602 Warsaw, Poland.
  • Wróblewska JP; Laboratory for Gene Therapy, Department of Cancer Immunology, Poznan University of Medical Sciences, 60-806 Poznan, Poland; Laboratory for Gene Therapy, Department of Diagnostics and Cancer Immunology, Greater Poland Cancer Centre, 61-866 Poznan, Poland.
  • Tomczak K; Laboratory for Gene Therapy, Department of Diagnostics and Cancer Immunology, Greater Poland Cancer Centre, 61-866 Poznan, Poland; Postgraduate School of Molecular Medicine, Medical University of Warsaw, 02-091 Warsaw, Poland.
  • Kulcenty K; Laboratory for Gene Therapy, Department of Cancer Immunology, Poznan University of Medical Sciences, 60-806 Poznan, Poland; Laboratory for Gene Therapy, Department of Diagnostics and Cancer Immunology, Greater Poland Cancer Centre, 61-866 Poznan, Poland.
  • Ploski R; Department of Medical Genetics, Medical University of Warsaw, 02-091 Warsaw, Poland.
  • Biecek P; Faculty of Mathematics and Information Science, Warsaw University of Technology, 00-602 Warsaw, Poland; Warsaw Faculty of Mathematics, Informatics, and Mechanics, University of Warsaw, 02-097 Warsaw, Poland.
  • Esteller M; Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona 08908, Catalonia, Spain; Physiological Sciences Department, School of Medicine and Health Sciences, University of Barcelona (UB), Barcelona 08907, Catalonia, Spain;
  • Shah PK; Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.
  • Rai K; Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA. Electronic address: krai@mdanderson.org.
  • Wiznerowicz M; Laboratory for Gene Therapy, Department of Cancer Immunology, Poznan University of Medical Sciences, 60-806 Poznan, Poland; Laboratory for Gene Therapy, Department of Diagnostics and Cancer Immunology, Greater Poland Cancer Centre, 61-866 Poznan, Poland. Electronic address: wiznerowicz@ump.edu.pl.
Stem Cell Reports ; 9(6): 2065-2080, 2017 12 12.
Article em En | MEDLINE | ID: mdl-29198826
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Diferenciação Celular / Células-Tronco Pluripotentes / Proteína 28 com Motivo Tripartido Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Diferenciação Celular / Células-Tronco Pluripotentes / Proteína 28 com Motivo Tripartido Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article