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Genomic Investigation of a Putative Endoscope-Associated Carbapenem-Resistant Enterobacter cloacae Outbreak Reveals a Wide Diversity of Circulating Strains and Resistance Mutations.
Hawken, Shawn E; Washer, Laraine L; Williams, Christopher L; Newton, Duane W; Snitkin, Evan S.
Afiliação
  • Hawken SE; Department of Microbiology and Immunology, University of Michigan Medical School.
  • Washer LL; Department of Internal Medicine, Division of Infectious Diseases.
  • Williams CL; Department of Pathology, University of Michigan Health System, Ann Arbor.
  • Newton DW; Department of Pathology, University of Michigan Health System, Ann Arbor.
  • Snitkin ES; Department of Microbiology and Immunology, University of Michigan Medical School.
Clin Infect Dis ; 66(3): 460-463, 2018 01 18.
Article em En | MEDLINE | ID: mdl-29211819
ABSTRACT
A genomic epidemiologic investigation of a putative carbapenem-resistant Enterobacter cloacae outbreak revealed few plausible instances of nosocomial transmission, highlighting instead the frequent importation of E. cloacae into our hospital. Searching for genetic determinants of carbapenem resistance demonstrated that most resistance is due to convergent mutations in phylogenetically diverse E. cloacae.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carbapenêmicos / Surtos de Doenças / Enterobacter cloacae / Farmacorresistência Bacteriana / Endoscopia Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carbapenêmicos / Surtos de Doenças / Enterobacter cloacae / Farmacorresistência Bacteriana / Endoscopia Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article