Synthesis of carbohydrate conjugated 6A,6D-bifunctionalized ß cyclodextrin derivatives as potential liver cancer drug carriers.
Carbohydr Polym
; 181: 957-963, 2018 Feb 01.
Article
em En
| MEDLINE
| ID: mdl-29254060
Galactosyl and lactosyl conjugated 6A,6D-bifunctionlized ß cyclodextrin derivatives were designed and synthesized as the potential liver cancer drug carriers through SN2 replacement and click reactions in order to increase liver cancer drug's targeting ability, solubility and stability. The synthetic methods and strategies to obtain the designed compounds were discussed.
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Base de dados:
MEDLINE
Assunto principal:
Carboidratos
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Portadores de Fármacos
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Beta-Ciclodextrinas
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Neoplasias Hepáticas
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article