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Synthesis of carbohydrate conjugated 6A,6D-bifunctionalized ß cyclodextrin derivatives as potential liver cancer drug carriers.
Ding, Yili; Vara Prasad, Chamakura V N S; Ding, Charles; Wang, Bingyun.
Afiliação
  • Ding Y; Life Science Department, Foshan University, Foshan, Guangdong, 528000, PR China. Electronic address: yiding93@yahoo.com.
  • Vara Prasad CVNS; Das Pharma, Turangi P.O., Kakinada, A.P., 533016, India.
  • Ding C; Piedmont Hill High School, San Jose, CA, 95132, USA.
  • Wang B; Life Science Department, Foshan University, Foshan, Guangdong, 528000, PR China.
Carbohydr Polym ; 181: 957-963, 2018 Feb 01.
Article em En | MEDLINE | ID: mdl-29254060
Galactosyl and lactosyl conjugated 6A,6D-bifunctionlized ß cyclodextrin derivatives were designed and synthesized as the potential liver cancer drug carriers through SN2 replacement and click reactions in order to increase liver cancer drug's targeting ability, solubility and stability. The synthetic methods and strategies to obtain the designed compounds were discussed.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carboidratos / Portadores de Fármacos / Beta-Ciclodextrinas / Neoplasias Hepáticas Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carboidratos / Portadores de Fármacos / Beta-Ciclodextrinas / Neoplasias Hepáticas Idioma: En Ano de publicação: 2018 Tipo de documento: Article