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Evolutionary action and structural basis of the allosteric switch controlling ß2AR functional selectivity.
Schönegge, Anne-Marie; Gallion, Jonathan; Picard, Louis-Philippe; Wilkins, Angela D; Le Gouill, Christian; Audet, Martin; Stallaert, Wayne; Lohse, Martin J; Kimmel, Marek; Lichtarge, Olivier; Bouvier, Michel.
Afiliação
  • Schönegge AM; Department of Biochemistry, Institute for Research in Immunology and Cancer, Université de Montreal, Montreal, QC, Canada.
  • Gallion J; Department of Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, TX, USA.
  • Picard LP; Department of Biochemistry, Institute for Research in Immunology and Cancer, Université de Montreal, Montreal, QC, Canada.
  • Wilkins AD; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
  • Le Gouill C; Department of Biochemistry, Institute for Research in Immunology and Cancer, Université de Montreal, Montreal, QC, Canada.
  • Audet M; Department of Biochemistry, Institute for Research in Immunology and Cancer, Université de Montreal, Montreal, QC, Canada.
  • Stallaert W; Department of Biochemistry, Institute for Research in Immunology and Cancer, Université de Montreal, Montreal, QC, Canada.
  • Lohse MJ; Institute of Pharmacology and Toxicology, Würzburg, Germany.
  • Kimmel M; Max Delbrück Center for Molecular Medicine, Berlin, Germany.
  • Lichtarge O; Departments of Statistics and Bioengineering, Rice University, Houston, TX, USA.
  • Bouvier M; Department of Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, TX, USA.
Nat Commun ; 8(1): 2169, 2017 12 18.
Article em En | MEDLINE | ID: mdl-29255305

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Receptores Adrenérgicos beta 2 / Evolução Molecular / Mutação Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Receptores Adrenérgicos beta 2 / Evolução Molecular / Mutação Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article