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New Cytotoxic Terpenoids from Soft Corals Nephthea chabroli and Paralemnalia thyrsoides.
Lee, Yu-Sheng; Duh, Tsai-Hui; Siao, Shu-Sheng; Chang, Rey-Chang; Wang, Shang-Kwei; Duh, Chang-Yih.
Afiliação
  • Lee YS; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan. m995020028@student.nsysu.edu.tw.
  • Duh TH; Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan. tshudu@kmu.edu.tw.
  • Siao SS; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan. m035020008@student.nsysu.edu.tw.
  • Chang RC; Department of Marine Biotechnology, National Kaohsiung Marine University, Kaohsiung 811, Taiwan. rcchang@mail.nkmu.edu.tw.
  • Wang SK; Department of Microbiology, Kaohsiung Medical University, Kaohsiung 807, Taiwan. skwang@cc.kmu.edu.tw.
  • Duh CY; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan. yihduh@mail.nsysu.edu.tw.
Mar Drugs ; 15(12)2017 Dec 19.
Article em En | MEDLINE | ID: mdl-29257046
ABSTRACT
A novel cytotoxic diterpenoid, chabrolin A (1) (possessing an unprecedented terpenoid skeleton), as well as three new cytotoxic sesquiterpenoids, parathyrsoidins E-G (2-4), were isolated by cytotoxicity-guided fractionation from soft corals Nephtheachabroli and Paralemnalia thyrsoides. The structures of the new compounds were determined by extensive analysis of spectroscopic data.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Terpenos / Antozoários / Antineoplásicos Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Terpenos / Antozoários / Antineoplásicos Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article