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Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions.
Wang, Tiansheng; Bemis, Guy; Hanzelka, Brian; Zuccola, Harmon; Wynn, Michael; Moody, Cameron Stuver; Green, Jeremy; Locher, Christopher; Liu, Aixiang; Gao, Hongwu; Xu, Yuzhou; Wang, Shaohui; Wang, Jie; Bennani, Youssef L; Thomson, John A; Müh, Ute.
Afiliação
  • Wang T; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, Massachusetts 02210, United States.
  • Bemis G; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, Massachusetts 02210, United States.
  • Hanzelka B; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, Massachusetts 02210, United States.
  • Zuccola H; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, Massachusetts 02210, United States.
  • Wynn M; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, Massachusetts 02210, United States.
  • Moody CS; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, Massachusetts 02210, United States.
  • Green J; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, Massachusetts 02210, United States.
  • Locher C; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, Massachusetts 02210, United States.
  • Liu A; Shanghai ChemPartner Co. Ltd., 998 Halei Road, Pudong New Area, Shanghai 201203, China.
  • Gao H; Shanghai ChemPartner Co. Ltd., 998 Halei Road, Pudong New Area, Shanghai 201203, China.
  • Xu Y; Shanghai ChemPartner Co. Ltd., 998 Halei Road, Pudong New Area, Shanghai 201203, China.
  • Wang S; Shanghai ChemPartner Co. Ltd., 998 Halei Road, Pudong New Area, Shanghai 201203, China.
  • Wang J; Shanghai ChemPartner Co. Ltd., 998 Halei Road, Pudong New Area, Shanghai 201203, China.
  • Bennani YL; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, Massachusetts 02210, United States.
  • Thomson JA; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, Massachusetts 02210, United States.
  • Müh U; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, Massachusetts 02210, United States.
ACS Med Chem Lett ; 8(12): 1224-1229, 2017 Dec 14.
Article em En | MEDLINE | ID: mdl-29259738
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article