Feeling Exhausted? Tuning Irf4 Energizes Dysfunctional T Cells.
Immunity
; 47(6): 1009-1011, 2017 12 19.
Article
em En
| MEDLINE
| ID: mdl-29262341
ABSTRACT
The regulatory mechanisms governing T cell exhaustion remain incompletely understood. Man et al. (2017) and Wu et al. (2017) report that the T cell receptor responsive transcription factor Irf4 promotes T cell exhaustion in chronic viral infection but dampens exhaustion in response to tissue allografts.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Receptores de Antígenos de Linfócitos T
/
Linfócitos T CD8-Positivos
Limite:
Humans
/
Male
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article