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Design of the First-in-Class, Highly Potent Irreversible Inhibitor Targeting the Menin-MLL Protein-Protein Interaction.
Xu, Shilin; Aguilar, Angelo; Xu, Tianfeng; Zheng, Ke; Huang, Liyue; Stuckey, Jeanne; Chinnaswamy, Krishnapriya; Bernard, Denzil; Fernández-Salas, Ester; Liu, Liu; Wang, Mi; McEachern, Donna; Przybranowski, Sally; Foster, Caroline; Wang, Shaomeng.
Afiliação
  • Xu S; Comprehensive Cancer and Departments of Internal Medicine, Pharmacology and Medicinal Chemistry, University of Michigan, 1600 Huron Parkway, Ann Arbor, MI, 48109, USA.
  • Aguilar A; Comprehensive Cancer and Departments of Internal Medicine, Pharmacology and Medicinal Chemistry, University of Michigan, 1600 Huron Parkway, Ann Arbor, MI, 48109, USA.
  • Xu T; Comprehensive Cancer and Departments of Internal Medicine, Pharmacology and Medicinal Chemistry, University of Michigan, 1600 Huron Parkway, Ann Arbor, MI, 48109, USA.
  • Zheng K; Comprehensive Cancer and Departments of Internal Medicine, Pharmacology and Medicinal Chemistry, University of Michigan, 1600 Huron Parkway, Ann Arbor, MI, 48109, USA.
  • Huang L; Comprehensive Cancer and Departments of Internal Medicine, Pharmacology and Medicinal Chemistry, University of Michigan, 1600 Huron Parkway, Ann Arbor, MI, 48109, USA.
  • Stuckey J; Life Sciences Institute, University of Michigan, 210 Washtenaw, Ann Arbor, MI, 48109, USA.
  • Chinnaswamy K; Life Sciences Institute, University of Michigan, 210 Washtenaw, Ann Arbor, MI, 48109, USA.
  • Bernard D; Comprehensive Cancer and Departments of Internal Medicine, Pharmacology and Medicinal Chemistry, University of Michigan, 1600 Huron Parkway, Ann Arbor, MI, 48109, USA.
  • Fernández-Salas E; Department of Pathology, University of Michigan, 1600 Huron Parkway, Ann Arbor, MI, 48109, USA.
  • Liu L; Comprehensive Cancer and Departments of Internal Medicine, Pharmacology and Medicinal Chemistry, University of Michigan, 1600 Huron Parkway, Ann Arbor, MI, 48109, USA.
  • Wang M; Comprehensive Cancer and Departments of Internal Medicine, Pharmacology and Medicinal Chemistry, University of Michigan, 1600 Huron Parkway, Ann Arbor, MI, 48109, USA.
  • McEachern D; Comprehensive Cancer and Departments of Internal Medicine, Pharmacology and Medicinal Chemistry, University of Michigan, 1600 Huron Parkway, Ann Arbor, MI, 48109, USA.
  • Przybranowski S; Comprehensive Cancer and Departments of Internal Medicine, Pharmacology and Medicinal Chemistry, University of Michigan, 1600 Huron Parkway, Ann Arbor, MI, 48109, USA.
  • Foster C; Comprehensive Cancer and Departments of Internal Medicine, Pharmacology and Medicinal Chemistry, University of Michigan, 1600 Huron Parkway, Ann Arbor, MI, 48109, USA.
  • Wang S; Comprehensive Cancer and Departments of Internal Medicine, Pharmacology and Medicinal Chemistry, University of Michigan, 1600 Huron Parkway, Ann Arbor, MI, 48109, USA.
Angew Chem Int Ed Engl ; 57(6): 1601-1605, 2018 02 05.
Article em En | MEDLINE | ID: mdl-29284071
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Histona-Lisina N-Metiltransferase / Proteínas Proto-Oncogênicas / Proteína de Leucina Linfoide-Mieloide / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Histona-Lisina N-Metiltransferase / Proteínas Proto-Oncogênicas / Proteína de Leucina Linfoide-Mieloide / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article