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Allosteric Coupling of Drug Binding and Intracellular Signaling in the A2A Adenosine Receptor.
Eddy, Matthew T; Lee, Ming-Yue; Gao, Zhan-Guo; White, Kate L; Didenko, Tatiana; Horst, Reto; Audet, Martin; Stanczak, Pawel; McClary, Kyle M; Han, Gye Won; Jacobson, Kenneth A; Stevens, Raymond C; Wüthrich, Kurt.
Afiliação
  • Eddy MT; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Departments of Biological Sciences and Chemistry, Bridge Institute, University of Southern California, Los Angeles, CA 90089, USA.
  • Lee MY; Departments of Biological Sciences and Chemistry, Bridge Institute, University of Southern California, Los Angeles, CA 90089, USA.
  • Gao ZG; Laboratory of Bioorganic Chemistry, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA.
  • White KL; Departments of Biological Sciences and Chemistry, Bridge Institute, University of Southern California, Los Angeles, CA 90089, USA.
  • Didenko T; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Horst R; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Pfizer Worldwide Research and Development, Eastern Point Road, Groton, CT 06340, USA.
  • Audet M; Departments of Biological Sciences and Chemistry, Bridge Institute, University of Southern California, Los Angeles, CA 90089, USA.
  • Stanczak P; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • McClary KM; Departments of Biological Sciences and Chemistry, Bridge Institute, University of Southern California, Los Angeles, CA 90089, USA.
  • Han GW; Departments of Biological Sciences and Chemistry, Bridge Institute, University of Southern California, Los Angeles, CA 90089, USA.
  • Jacobson KA; Laboratory of Bioorganic Chemistry, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA.
  • Stevens RC; Departments of Biological Sciences and Chemistry, Bridge Institute, University of Southern California, Los Angeles, CA 90089, USA.
  • Wüthrich K; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Skaggs Institute of Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: wuthrich@scripps.edu.
Cell ; 172(1-2): 68-80.e12, 2018 01 11.
Article em En | MEDLINE | ID: mdl-29290469
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Receptor A2A de Adenosina / Regulação Alostérica Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Receptor A2A de Adenosina / Regulação Alostérica Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article