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Design of Aminobenzothiazole Inhibitors of Rho Kinases 1 and 2 by Using Protein Kinase A as a Structure Surrogate.
Judge, Russell A; Vasudevan, Anil; Scott, Victoria E; Simler, Gricelda H; Pratt, Steve D; Namovic, Marian T; Putman, C Brent; Aguirre, Ana; Stoll, Vincent S; Mamo, Mulugeta; Swann, Steven I; Cassar, Steven C; Faltynek, Connie R; Kage, Karen L; Boyce-Rustay, Janel M; Hobson, Adrian D.
Afiliação
  • Judge RA; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA.
  • Vasudevan A; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA.
  • Scott VE; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA.
  • Simler GH; AbbVie Bioresearch Center, 100 Research Drive, Worcester, MA, 01605, USA.
  • Pratt SD; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA.
  • Namovic MT; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA.
  • Putman CB; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA.
  • Aguirre A; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA.
  • Stoll VS; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA.
  • Mamo M; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA.
  • Swann SI; Current address: Novartis Institute for Biomedical Research, 4560 Horton Street, Emeryville, CA, 94608, USA.
  • Cassar SC; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA.
  • Faltynek CR; Current address: Takeda Pharmaceuticals, 10410 Science Center Drive, San Diego, CA, 92121, USA.
  • Kage KL; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA.
  • Boyce-Rustay JM; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA.
  • Hobson AD; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA.
Chembiochem ; 19(6): 613-621, 2018 03 16.
Article em En | MEDLINE | ID: mdl-29314498
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Inibidores de Proteínas Quinases / Benzotiazóis / Quinases Associadas a rho Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Inibidores de Proteínas Quinases / Benzotiazóis / Quinases Associadas a rho Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article