Synthetic Strategy toward the Pentacyclic Core of Melodinus Alkaloids.
J Org Chem
; 83(4): 2244-2249, 2018 02 16.
Article
em En
| MEDLINE
| ID: mdl-29338221
ABSTRACT
The three-component Povarov reaction is efficiently utilized for construction of the pentacyclic framework of complex Melodinus alkaloids, which is amenable to expansion to other complex natural products. The key steps were Povarov reaction, one-pot reductive cyclization, and ring-closing metathesis (RCM) reaction.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Compostos Policíclicos
/
Quinolinas
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Apocynaceae
/
Alcaloides
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article