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A Novel l-Asparaginase with low l-Glutaminase Coactivity Is Highly Efficacious against Both T- and B-cell Acute Lymphoblastic Leukemias In Vivo.
Nguyen, Hien Anh; Su, Ying; Zhang, Jenny Y; Antanasijevic, Aleksandar; Caffrey, Michael; Schalk, Amanda M; Liu, Li; Rondelli, Damiano; Oh, Annie; Mahmud, Dolores L; Bosland, Maarten C; Kajdacsy-Balla, Andre; Peirs, Sofie; Lammens, Tim; Mondelaers, Veerle; De Moerloose, Barbara; Goossens, Steven; Schlicht, Michael J; Kabirov, Kasim K; Lyubimov, Alexander V; Merrill, Bradley J; Saunthararajah, Yogen; Van Vlierberghe, Pieter; Lavie, Arnon.
Afiliação
  • Nguyen HA; The Jesse Brown VA Medical Center, Chicago, Illinois.
  • Su Y; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,.
  • Zhang JY; The Jesse Brown VA Medical Center, Chicago, Illinois.
  • Antanasijevic A; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,.
  • Caffrey M; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,.
  • Schalk AM; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,.
  • Liu L; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,.
  • Rondelli D; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,.
  • Oh A; Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, Illinois.
  • Mahmud DL; Division of Hematology/Oncology, University of Illinois Hospital and Health Sciences System, Chicago, Illinois.
  • Bosland MC; Division of Hematology/Oncology, University of Illinois Hospital and Health Sciences System, Chicago, Illinois.
  • Kajdacsy-Balla A; Division of Hematology/Oncology, University of Illinois Hospital and Health Sciences System, Chicago, Illinois.
  • Peirs S; Department of Pathology, University of Illinois at Chicago, Chicago, Illinois.
  • Lammens T; Department of Pathology, University of Illinois at Chicago, Chicago, Illinois.
  • Mondelaers V; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.
  • De Moerloose B; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
  • Goossens S; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
  • Schlicht MJ; Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium.
  • Kabirov KK; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
  • Lyubimov AV; Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium.
  • Merrill BJ; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
  • Saunthararajah Y; Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium.
  • Van Vlierberghe P; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.
  • Lavie A; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
Cancer Res ; 78(6): 1549-1560, 2018 03 15.
Article em En | MEDLINE | ID: mdl-29343523
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asparaginase / Proteínas Recombinantes / Leucemia-Linfoma Linfoblástico de Células Precursoras B / Leucemia-Linfoma Linfoblástico de Células T Precursoras / Antineoplásicos Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asparaginase / Proteínas Recombinantes / Leucemia-Linfoma Linfoblástico de Células Precursoras B / Leucemia-Linfoma Linfoblástico de Células T Precursoras / Antineoplásicos Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article