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An improved method of crafting a multi-electrode spiral cuff for the selective.
Rozman, Janez; Peclin, Polona; Ribaric, Samo; Godec, Matjaz; Burja, Jaka.
Afiliação
  • Rozman J; Center for Implantable Technology and Sensors, ITIS d. o. o. Ljubljana, Lepi pot 11, 1000, Ljubljana, Slovenia.
  • Peclin P; Institute of Pathophysiology, Medical Faculty, University of Ljubljana, Vrazov trg 2, 1000, Ljubljana, Slovenia.
  • Ribaric S; Center for Implantable Technology and Sensors, ITIS d. o. o. Ljubljana, Lepi pot 11, 1000, Ljubljana, Slovenia.
  • Godec M; Institute of Pathophysiology, Medical Faculty, University of Ljubljana, Vrazov trg 2, 1000, Ljubljana, Slovenia.
  • Burja J; Institute of Metals and Technology, Lepi pot 11, 1000, Ljubljana, Slovenia. matjaz.godec@imt.si.
Sci Rep ; 8(1): 915, 2018 01 17.
Article em En | MEDLINE | ID: mdl-29343774
ABSTRACT
This article reviews an improved methodology and technology for crafting a multi-electrode spiral cuff for the selective activation of nerve fibres in particular superficial regions of a peripheral nerve. The analysis, structural and mechanical properties of the spot welds used for the interconnections between the stimulating electrodes and stainless-steel lead wires are presented. The cuff consisted of 33 platinum electrodes embedded within a self-curling 17-mm-long silicone spiral sheet with a nominal internal diameter of 2.5 mm. The weld was analyzed using scanning electron microscopy and nanohardness tests, while the interconnection was investigated using destructive load tests. The functionality of the cuff was tested in an isolated porcine vagus nerve. The results of the scanning electron microscopy show good alloying and none of the typical welding defects that occur between the wire and the platinum foil. The results of the destructive load tests show that the breaking loads were between 3.22 and 5 N. The results of the nanohardness testing show that the hardness of the weld was different for the particular sites on the weld sample. Finally, the results of the functional testing show that for different stimulation intensities both the compound action potential deflection and the shape are modulated.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nervos Periféricos / Nervo Vago / Eletroquímica / Desenho de Equipamento Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nervos Periféricos / Nervo Vago / Eletroquímica / Desenho de Equipamento Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article