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Cerebral organoids derived from Sandhoff disease-induced pluripotent stem cells exhibit impaired neurodifferentiation.
Allende, Maria L; Cook, Emily K; Larman, Bridget C; Nugent, Adrienne; Brady, Jacqueline M; Golebiowski, Diane; Sena-Esteves, Miguel; Tifft, Cynthia J; Proia, Richard L.
Afiliação
  • Allende ML; Genetics of Development and Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Cook EK; Genetics of Development and Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Larman BC; Genetics of Development and Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Nugent A; Genetics of Development and Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Brady JM; National Institutes of Health Undiagnosed Diseases Program, National Institutes of Health Office of Rare Diseases Research and National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892.
  • Golebiowski D; Department of Neurology and Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605.
  • Sena-Esteves M; Department of Neurology and Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605.
  • Tifft CJ; National Institutes of Health Undiagnosed Diseases Program, National Institutes of Health Office of Rare Diseases Research and National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892.
  • Proia RL; Genetics of Development and Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 richardp@intra.niddk.nih.gov.
J Lipid Res ; 59(3): 550-563, 2018 03.
Article em En | MEDLINE | ID: mdl-29358305
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Sandhoff / Organoides / Diferenciação Celular / Córtex Cerebral / Células-Tronco Pluripotentes Induzidas / Neurônios Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Sandhoff / Organoides / Diferenciação Celular / Córtex Cerebral / Células-Tronco Pluripotentes Induzidas / Neurônios Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article