Novel Function of Cyclooxygenase-2: Suppressing Mycobacteria by Promoting Autophagy via the Protein Kinase B/Mammalian Target of Rapamycin Pathway.

Xiong, Wenjing; Wen, Qian; Du, Xialin; Wang, Jinli; He, Wenting; Wang, Ruining; Hu, Shengfeng; Zhou, Xinying; Yang, Jiahui; Gao, Yuchi; Ma, Li

Xiong, Wenjing; Wen, Qian; Du, Xialin; Wang, Jinli; He, Wenting; Wang, Ruining; Hu, Shengfeng; Zhou, Xinying; Yang, Jiahui; Gao, Yuchi; Ma, Li.

Afiliação

Xiong W; Institute of Molecular Immunology, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
Wen Q; Institute of Molecular Immunology, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
Du X; Institute of Molecular Immunology, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
Wang J; Institute of Molecular Immunology, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
He W; Institute of Molecular Immunology, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
Wang R; Institute of Molecular Immunology, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
Hu S; Institute of Molecular Immunology, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
Zhou X; Institute of Molecular Immunology, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
Yang J; Institute of Molecular Immunology, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
Gao Y; Institute of Molecular Immunology, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
Ma L; Institute of Molecular Immunology, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.

J Infect Dis ; 217(8): 1267-1279, 2018 03 28.

Article em En | MEDLINE | ID: mdl-29373690

Assuntos

Ciclo-Oxigenase 2/metabolismo; Mycobacterium tuberculosis/fisiologia; Proteínas Proto-Oncogênicas c-akt/metabolismo; Transdução de Sinais/fisiologia; Serina-Treonina Quinases TOR/metabolismo; Animais; Autofagia; Regulação Enzimológica da Expressão Gênica; Gliceraldeído-3-Fosfato Desidrogenase (Fosforiladora)/genética; Gliceraldeído-3-Fosfato Desidrogenase (Fosforiladora)/metabolismo; Macrófagos/metabolismo; Camundongos; Viabilidade Microbiana; Prostaglandinas/metabolismo; Proteínas Proto-Oncogênicas c-akt/genética; Células RAW 264.7

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Ciclo-Oxigenase 2 / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Mycobacterium tuberculosis Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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