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Single cell analysis of Crohn's disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties.
Suzuki, Kohei; Murano, Tatsuro; Shimizu, Hiromichi; Ito, Go; Nakata, Toru; Fujii, Satoru; Ishibashi, Fumiaki; Kawamoto, Ami; Anzai, Sho; Kuno, Reiko; Kuwabara, Konomi; Takahashi, Junichi; Hama, Minami; Nagata, Sayaka; Hiraguri, Yui; Takenaka, Kento; Yui, Shiro; Tsuchiya, Kiichiro; Nakamura, Tetsuya; Ohtsuka, Kazuo; Watanabe, Mamoru; Okamoto, Ryuichi.
Afiliação
  • Suzuki K; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Murano T; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Shimizu H; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Ito G; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Nakata T; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Fujii S; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Ishibashi F; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Kawamoto A; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Anzai S; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Kuno R; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Kuwabara K; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Takahashi J; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Hama M; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Nagata S; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Hiraguri Y; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Takenaka K; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Yui S; Center for Stem Cell and Regenerative Medicine, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.
  • Tsuchiya K; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Nakamura T; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Ohtsuka K; Department of Advanced Therapeutics in GI Diseases, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Watanabe M; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
  • Okamoto R; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.
J Gastroenterol ; 53(9): 1035-1047, 2018 Sep.
Article em En | MEDLINE | ID: mdl-29374777
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco / Doença de Crohn / Organoides / Análise de Célula Única / Intestino Delgado Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco / Doença de Crohn / Organoides / Análise de Célula Única / Intestino Delgado Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article