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A tri-serine cluster within the topoisomerase IIα-interaction domain of the BLM helicase is required for regulating chromosome breakage in human cells.
Behnfeldt, Julia Harris; Acharya, Samir; Tangeman, Larissa; Gocha, April Sandy; Keirsey, Jeremy; Groden, Joanna.
Afiliação
  • Behnfeldt JH; Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
  • Acharya S; Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
  • Tangeman L; Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
  • Gocha AS; Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
  • Keirsey J; Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
  • Groden J; Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
Hum Mol Genet ; 27(7): 1241-1251, 2018 04 01.
Article em En | MEDLINE | ID: mdl-29385443
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA Topoisomerases Tipo II / Quebra Cromossômica / Instabilidade Cromossômica / RecQ Helicases / Proteínas de Ligação a Poli-ADP-Ribose Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA Topoisomerases Tipo II / Quebra Cromossômica / Instabilidade Cromossômica / RecQ Helicases / Proteínas de Ligação a Poli-ADP-Ribose Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article