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The Synthesized Plant Metabolite 3,4,5-Tri-O-Galloylquinic Acid Methyl Ester Inhibits Calcium Oxalate Crystal Growth in a Drosophila Model, Downregulates Renal Cell Surface Annexin A1 Expression, and Decreases Crystal Adhesion to Cells.
Abd El-Salam, Mohamed; Bastos, Jairo Kenupp; Han, Jing Jing; Previdi, Daniel; Coelho, Eduardo B; Donate, Paulo M; Romero, Michael F; Lieske, John.
Afiliação
  • Abd El-Salam M; Department of Pharmaceutical Sciences, School of Pharmaceutical Sciences, University of São Paulo , Ribeirão Preto, São Paulo 14040-903, Brazil.
  • Bastos JK; Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic College of Medicine , Rochester, Minnesota 55905, United States.
  • Han JJ; Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine , Rochester, Minnesota 55905, United States.
  • Previdi D; Department of Pharmaceutical Sciences, School of Pharmaceutical Sciences, University of São Paulo , Ribeirão Preto, São Paulo 14040-903, Brazil.
  • Coelho EB; Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic College of Medicine , Rochester, Minnesota 55905, United States.
  • Donate PM; Department of Chemistry, Faculty of Philosophy, Arts and Sciences, University of São Paulo , Ribeirão Preto, São Paulo 14040-901, Brazil.
  • Romero MF; Department of Clinical Medicine, School of Medicine of Ribeirão Preto, University of São Paulo , Ribeirão Preto, São Paulo 14040-900, Brazil.
  • Lieske J; Department of Chemistry, Faculty of Philosophy, Arts and Sciences, University of São Paulo , Ribeirão Preto, São Paulo 14040-901, Brazil.
J Med Chem ; 61(4): 1609-1621, 2018 02 22.
Article em En | MEDLINE | ID: mdl-29406740
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Quínico / Oxalato de Cálcio / Adesão Celular / Anexina A1 / Ácido Gálico Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Quínico / Oxalato de Cálcio / Adesão Celular / Anexina A1 / Ácido Gálico Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article