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Enhancer redundancy provides phenotypic robustness in mammalian development.
Osterwalder, Marco; Barozzi, Iros; Tissières, Virginie; Fukuda-Yuzawa, Yoko; Mannion, Brandon J; Afzal, Sarah Y; Lee, Elizabeth A; Zhu, Yiwen; Plajzer-Frick, Ingrid; Pickle, Catherine S; Kato, Momoe; Garvin, Tyler H; Pham, Quan T; Harrington, Anne N; Akiyama, Jennifer A; Afzal, Veena; Lopez-Rios, Javier; Dickel, Diane E; Visel, Axel; Pennacchio, Len A.
Afiliação
  • Osterwalder M; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.
  • Barozzi I; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.
  • Tissières V; Department of Biomedicine, University of Basel, 4058 Basel, Switzerland.
  • Fukuda-Yuzawa Y; Centro Andaluz de Biología del Desarrollo, CSIC/JA/Universidad Pablo de Olavide, 41013 Seville, Spain.
  • Mannion BJ; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.
  • Afzal SY; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.
  • Lee EA; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.
  • Zhu Y; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.
  • Plajzer-Frick I; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.
  • Pickle CS; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.
  • Kato M; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.
  • Garvin TH; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.
  • Pham QT; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.
  • Harrington AN; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.
  • Akiyama JA; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.
  • Afzal V; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.
  • Lopez-Rios J; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.
  • Dickel DE; Department of Biomedicine, University of Basel, 4058 Basel, Switzerland.
  • Visel A; Centro Andaluz de Biología del Desarrollo, CSIC/JA/Universidad Pablo de Olavide, 41013 Seville, Spain.
  • Pennacchio LA; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.
Nature ; 554(7691): 239-243, 2018 02 08.
Article em En | MEDLINE | ID: mdl-29420474
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenótipo / Elementos Facilitadores Genéticos / Regulação da Expressão Gênica no Desenvolvimento / Extremidades Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenótipo / Elementos Facilitadores Genéticos / Regulação da Expressão Gênica no Desenvolvimento / Extremidades Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article