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Inhaled hexadecyl-treprostinil provides pulmonary vasodilator activity at significantly lower plasma concentrations than infused treprostinil.
Chapman, Richard W; Li, Zhili; Corboz, Michel R; Gauani, Helena; Plaunt, Adam J; Konicek, Donna M; Leifer, Franziska G; Laurent, Charles E; Yin, Han; Salvail, Dany; Dziak, Chad; Perkins, Walter R; Malinin, Vladimir.
Afiliação
  • Chapman RW; Insmed Incorporated, Bridgewater, NJ 08807, USA. Electronic address: richard.chapman@insmed.com.
  • Li Z; Insmed Incorporated, Bridgewater, NJ 08807, USA.
  • Corboz MR; Insmed Incorporated, Bridgewater, NJ 08807, USA.
  • Gauani H; Insmed Incorporated, Bridgewater, NJ 08807, USA.
  • Plaunt AJ; Insmed Incorporated, Bridgewater, NJ 08807, USA.
  • Konicek DM; Insmed Incorporated, Bridgewater, NJ 08807, USA.
  • Leifer FG; Insmed Incorporated, Bridgewater, NJ 08807, USA.
  • Laurent CE; IPS Therapeutique Incorporated, Sherbrooke, QC J1G5J6, Canada.
  • Yin H; IPS Therapeutique Incorporated, Sherbrooke, QC J1G5J6, Canada.
  • Salvail D; IPS Therapeutique Incorporated, Sherbrooke, QC J1G5J6, Canada.
  • Dziak C; Envigo CRS Incorporated, East Millstone, NJ 08873, USA.
  • Perkins WR; Insmed Incorporated, Bridgewater, NJ 08807, USA.
  • Malinin V; Insmed Incorporated, Bridgewater, NJ 08807, USA.
Pulm Pharmacol Ther ; 49: 104-111, 2018 04.
Article em En | MEDLINE | ID: mdl-29421665
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vasodilatação / Epoprostenol / Nanopartículas / Anti-Hipertensivos Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vasodilatação / Epoprostenol / Nanopartículas / Anti-Hipertensivos Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article