Respiratory syncytial virus prolifically infects N2a neuronal cells, leading to TLR4 and nucleolin protein modulations and RSV F protein co-localization with TLR4 and nucleolin.

Yuan, Xiaoling; Hu, Tao; He, Hanwen; Qiu, Huan; Wu, Xuan; Chen, Jingxian; Wang, Minmin; Chen, Cheng; Huang, Shenghai

Yuan, Xiaoling; Hu, Tao; He, Hanwen; Qiu, Huan; Wu, Xuan; Chen, Jingxian; Wang, Minmin; Chen, Cheng; Huang, Shenghai.

Afiliação

Yuan X; Department of Microbiology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui Province, 230032, People's Republic of China.
Hu T; Department of Microbiology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui Province, 230032, People's Republic of China.
He H; Department of Laboratory Medicine, Anhui Health College, Chizhou, Anhui Province, 247099, People's Republic of China.
Qiu H; Department of Microbiology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui Province, 230032, People's Republic of China.
Wu X; Department of Microbiology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui Province, 230032, People's Republic of China.
Chen J; Department of Microbiology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui Province, 230032, People's Republic of China.
Wang M; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA.
Chen C; Department of Microbiology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui Province, 230032, People's Republic of China.
Huang S; Department of Clinical Medicine, Anhui Medical University, Hefei, Anhui Province, 230032, People's Republic of China.

J Biomed Sci ; 25(1): 13, 2018 Feb 10.

Article em En | MEDLINE | ID: mdl-29427996

Assuntos

Fosfoproteínas/genética; Proteínas de Ligação a RNA/genética; Infecções por Vírus Respiratório Sincicial/genética; Vírus Sincicial Respiratório Humano/fisiologia; Receptor 4 Toll-Like/genética; Proteínas Virais de Fusão/genética; Animais; Linhagem Celular Tumoral; Glicoproteínas de Membrana/genética; Glicoproteínas de Membrana/metabolismo; Camundongos; Neuroblastoma; Fosfoproteínas/metabolismo; Proteínas de Ligação a RNA/metabolismo; Infecções por Vírus Respiratório Sincicial/fisiopatologia; Infecções por Vírus Respiratório Sincicial/virologia; Receptor 3 Toll-Like/genética; Receptor 3 Toll-Like/metabolismo; Receptor 4 Toll-Like/metabolismo; Receptor 7 Toll-Like/genética; Receptor 7 Toll-Like/metabolismo; Proteínas Virais de Fusão/metabolismo; Nucleolina

Palavras-chave

N2a cells; Nucleolin (C23); Respiratory syncytial virus (RSV); Toll-like receptor 4 (TLR4); Virus infection

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Proteínas Virais de Fusão / Proteínas de Ligação a RNA / Vírus Sincicial Respiratório Humano / Infecções por Vírus Respiratório Sincicial / Receptor 4 Toll-Like Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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