Benzodiazepine Use in Older Adults in the United States, Ontario, and Australia from 2010 to 2016.
J Am Geriatr Soc
; 66(6): 1180-1185, 2018 07.
Article
em En
| MEDLINE
| ID: mdl-29430639
ABSTRACT
OBJECTIVES:
To detail annual trends in benzodiazepine incidence and prevalence in older adults between 2010 and 2016 in three countries.DESIGN:
Observational multicountry cohort study with harmonized study protocol.SETTING:
The United States (veteran population); Ontario, Canada; and Australia.PARTICIPANTS:
All people aged 65 and older (8,270,000 people). MEASUREMENTS Annual incidence and prevalence of benzodiazepine use stratified according to age group (65-74, 75-84, ≥85) and sex. We performed multiple regression analyses to assess whether rates of incident and prevalent use changed significantly over time.RESULTS:
Over the study period, we observed a significant decrease in incident benzodiazepine use in the United States (2.6% to 1.7%) and Ontario (6.0% to 4.4%) but not Australia (7.0% to 6.7%). We found significant declines in prevalent use in all countries (United States 9.2% to 7.3%; Ontario 18.2% to 13.4%; Australia 20.2% to 16.8%). Although incidence and prevalence increased with age in Ontario and Australia, they decreased with age in the United States. Incidence and prevalence were higher in women in all countries.CONCLUSION:
Consistent with other international studies, there have been small but significant reductions in the incidence and prevalence of benzodiazepine use in older adults in all three countries, with the exception of incidence in Australia, although use remains inappropriately high-particularly in those aged 85 and older-which warrants further attention from clinicians and policy-makers.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Benzodiazepinas
/
Padrões de Prática Médica
/
Revisão de Uso de Medicamentos
/
Uso Excessivo de Medicamentos Prescritos
Tipo de estudo:
Clinical_trials
/
Guideline
/
Incidence_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
País como assunto:
America do norte
/
Oceania
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article