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Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation.
Iorgulescu, J Bryan; Van Ziffle, Jessica; Stevers, Meredith; Grenert, James P; Bastian, Boris C; Chavez, Lukas; Stichel, Damian; Buchhalter, Ivo; Samuel, David; Nicolaides, Theodore; Banerjee, Anuradha; Mueller, Sabine; Gupta, Nalin; Tihan, Tarik; Bollen, Andrew W; Northcott, Paul A; Kool, Marcel; Pfister, Stefan; Korshunov, Andrey; Perry, Arie; Solomon, David A.
Afiliação
  • Iorgulescu JB; Department of Pathology, University of California, San Francisco, 513 Parnassus Ave, Health Sciences West 451, San Francisco, CA, 94143, USA.
  • Van Ziffle J; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Stevers M; Department of Pathology, University of California, San Francisco, 513 Parnassus Ave, Health Sciences West 451, San Francisco, CA, 94143, USA.
  • Grenert JP; Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA.
  • Bastian BC; Department of Pathology, University of California, San Francisco, 513 Parnassus Ave, Health Sciences West 451, San Francisco, CA, 94143, USA.
  • Chavez L; Department of Pathology, University of California, San Francisco, 513 Parnassus Ave, Health Sciences West 451, San Francisco, CA, 94143, USA.
  • Stichel D; Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA.
  • Buchhalter I; Department of Pathology, University of California, San Francisco, 513 Parnassus Ave, Health Sciences West 451, San Francisco, CA, 94143, USA.
  • Samuel D; Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA.
  • Nicolaides T; Hopp Children's Cancer Center, NCT Heidelberg (KiTZ), Heidelberg, Germany.
  • Banerjee A; Division of Pediatric Neuro-oncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Mueller S; Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany.
  • Gupta N; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Tihan T; Division of Pediatric Neuro-oncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Bollen AW; Division of Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Northcott PA; Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB), Heidelberg University, Heidelberg, Germany.
  • Kool M; Division of Pediatric Hematology/Oncology, Valley Children's Hospital, Madera, CA, USA.
  • Pfister S; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, CA, USA.
  • Korshunov A; Department of Neurological Surgery, University of California, San Francisco, CA, USA.
  • Perry A; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, CA, USA.
  • Solomon DA; Department of Neurological Surgery, University of California, San Francisco, CA, USA.
Acta Neuropathol ; 135(4): 635-638, 2018 04.
Article em En | MEDLINE | ID: mdl-29435664
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cerebelares / Proteínas Wnt / Proteínas Hedgehog / Meduloblastoma Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cerebelares / Proteínas Wnt / Proteínas Hedgehog / Meduloblastoma Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article