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The AMPK-PGC-1α signaling axis regulates the astrocyte glutathione system to protect against oxidative and metabolic injury.
Guo, Xiaoxin; Jiang, Qi; Tuccitto, Alessandra; Chan, Darren; Alqawlaq, Samih; Won, Gah-Jone; Sivak, Jeremy M.
Afiliação
  • Guo X; Krembil Research Institute, University Health Network, Toronto, Ontario, Canada; Department of Ophthalmology and Vision Science, University of Toronto, Toronto, Ontario, Canada.
  • Jiang Q; Krembil Research Institute, University Health Network, Toronto, Ontario, Canada; Department of Ophthalmology and Vision Science, University of Toronto, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
  • Tuccitto A; Krembil Research Institute, University Health Network, Toronto, Ontario, Canada; Department of Ophthalmology and Vision Science, University of Toronto, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
  • Chan D; Krembil Research Institute, University Health Network, Toronto, Ontario, Canada; Department of Ophthalmology and Vision Science, University of Toronto, Toronto, Ontario, Canada.
  • Alqawlaq S; Krembil Research Institute, University Health Network, Toronto, Ontario, Canada; Department of Ophthalmology and Vision Science, University of Toronto, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
  • Won GJ; Krembil Research Institute, University Health Network, Toronto, Ontario, Canada; Department of Ophthalmology and Vision Science, University of Toronto, Toronto, Ontario, Canada.
  • Sivak JM; Krembil Research Institute, University Health Network, Toronto, Ontario, Canada; Department of Ophthalmology and Vision Science, University of Toronto, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. Electronic address: j
Neurobiol Dis ; 113: 59-69, 2018 05.
Article em En | MEDLINE | ID: mdl-29438738
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Astrócitos / Estresse Oxidativo / Metabolismo Energético / Proteínas Quinases Ativadas por AMP / Coativador 1-alfa do Receptor gama Ativado por Proliferador de Peroxissomo / Glutationa Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Astrócitos / Estresse Oxidativo / Metabolismo Energético / Proteínas Quinases Ativadas por AMP / Coativador 1-alfa do Receptor gama Ativado por Proliferador de Peroxissomo / Glutationa Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article