The cytotoxicity of coxsackievirus B3 is associated with a blockage of autophagic flux mediated by reduced syntaxin 17 expression.

Tian, Lang; Yang, Yeyi; Li, Chunyun; Chen, Jia; Li, Zhuoying; Li, Xin; Li, Shentang; Wu, Fang; Hu, Zhangxue; Yang, Zuocheng

Tian, Lang; Yang, Yeyi; Li, Chunyun; Chen, Jia; Li, Zhuoying; Li, Xin; Li, Shentang; Wu, Fang; Hu, Zhangxue; Yang, Zuocheng.

Afiliação

Tian L; Department of Pediatrics, The Third Xiangya Hospital, Central South University, 410013, Changsha, China.
Yang Y; Department of Medicine, The Third Xiangya Hospital, Central South University, 410013, Changsha, China.
Li C; Department of Pediatrics, The Third Xiangya Hospital, Central South University, 410013, Changsha, China.
Chen J; Department of Pediatrics, The Third Xiangya Hospital, Central South University, 410013, Changsha, China.
Li Z; Department of Pediatrics, The Third Xiangya Hospital, Central South University, 410013, Changsha, China.
Li X; Department of Pediatrics, The Third Xiangya Hospital, Central South University, 410013, Changsha, China.
Li S; Department of Pediatrics, The Third Xiangya Hospital, Central South University, 410013, Changsha, China.
Wu F; Department of Pediatrics, Daping Hospital and Field Surgery Institute, Third Military Medical University, 400042, Chongqing, China.
Hu Z; Department of Pediatrics, Daping Hospital and Field Surgery Institute, Third Military Medical University, 400042, Chongqing, China. Huzx1@163.com.
Yang Z; Department of Pediatrics, The Third Xiangya Hospital, Central South University, 410013, Changsha, China. yangzuocheng2017@163.com.

Cell Death Dis ; 9(2): 242, 2018 02 14.

Article em En | MEDLINE | ID: mdl-29445155

Assuntos

Autofagossomos/metabolismo; Autofagia/genética; Enterovirus Humano B/patogenicidade; Interações Hospedeiro-Patógeno/genética; Lisossomos/metabolismo; Proteínas Qa-SNARE/genética; Apoptose/genética; Autofagossomos/virologia; Catepsina B/genética; Catepsina B/metabolismo; Catepsina L/genética; Catepsina L/metabolismo; Misturas Complexas/química; Enterovirus Humano B/fisiologia; Regulação da Expressão Gênica; Células HeLa; Humanos; Lisossomos/virologia; Fusão de Membrana; Octoxinol; Biossíntese de Proteínas; Proteínas Qa-SNARE/metabolismo; Transdução de Sinais; Replicação Viral

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Enterovirus Humano B / Proteínas Qa-SNARE / Interações Hospedeiro-Patógeno / Autofagossomos / Lisossomos Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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