Comparative evaluation of pharmacokinetics and pharmacodynamics of insulin glargine (Glaritus<sup>®</sup>) and Lantus<sup>®</sup> in healthy subjects: a double-blind, randomized clamp study.

Bhatia, Ashima; Tawade, Shraddha; Mastim, Mushtaque; Kitabi, Eliford Ngaimisi; Gopalakrishnan, Mathangi; Shah, Manish; Yeshamaina, Sridhar; Gobburu, Joga; Sahib, Maharaj; Thakur, Dipak; Prasanna Kumar, K M

Comparative evaluation of pharmacokinetics and pharmacodynamics of insulin glargine (Glaritus^®) and Lantus^® in healthy subjects: a double-blind, randomized clamp study.

Bhatia, Ashima; Tawade, Shraddha; Mastim, Mushtaque; Kitabi, Eliford Ngaimisi; Gopalakrishnan, Mathangi; Shah, Manish; Yeshamaina, Sridhar; Gobburu, Joga; Sahib, Maharaj; Thakur, Dipak; Prasanna Kumar, K M.

Afiliação

Bhatia A; Wockhardt, Global Clinical Development, BKC, Mumbai, India.
Tawade S; Wockhardt, Global Clinical Development, BKC, Mumbai, India.
Mastim M; Wockhardt, Global Clinical Development, BKC, Mumbai, India.
Kitabi EN; School of Pharmacy, Center for Translational Medicine, University of Maryland, 20 N. Pine Street, Baltimore, MD, 21201, USA.
Gopalakrishnan M; School of Pharmacy, Center for Translational Medicine, University of Maryland, 20 N. Pine Street, Baltimore, MD, 21201, USA. mgopalakrishnan@rx.umaryland.edu.
Shah M; Wockhardt, Global Clinical Development, BKC, Mumbai, India.
Yeshamaina S; Wockhardt, Global Clinical Development, BKC, Mumbai, India.
Gobburu J; School of Pharmacy, Center for Translational Medicine, University of Maryland, 20 N. Pine Street, Baltimore, MD, 21201, USA.
Sahib M; Wockhardt, Research Center, Aurangabad, India.
Thakur D; Wockhardt, Research Center, Aurangabad, India.
Prasanna Kumar KM; Centre for Diabetes and Endocrine Care, Bengaluru, India.

Acta Diabetol ; 55(5): 461-468, 2018 May.

Article em En | MEDLINE | ID: mdl-29453671

Assuntos

Hipoglicemiantes/farmacocinética; Insulina Glargina/farmacocinética; Adolescente; Adulto; Área Sob a Curva; Glicemia/efeitos dos fármacos; Glicemia/metabolismo; Estudos Cross-Over; Método Duplo-Cego; Feminino; Técnica Clamp de Glucose; Voluntários Saudáveis; Humanos; Hipoglicemiantes/administração & dosagem; Insulina/administração & dosagem; Insulina Glargina/administração & dosagem; Masculino; Pessoa de Meia-Idade; Adulto Jovem

Palavras-chave

Bioequivalence; Diabetes mellitus; Insulin glargine; Pharmacodynamics; Pharmacokinetics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Insulina Glargina / Hipoglicemiantes Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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