Identification of piRNA Binding Sites Reveals the Argonaute Regulatory Landscape of the C. elegans Germline.

Shen, En-Zhi; Chen, Hao; Ozturk, Ahmet R; Tu, Shikui; Shirayama, Masaki; Tang, Wen; Ding, Yue-He; Dai, Si-Yuan; Weng, Zhiping; Mello, Craig C

Identification of piRNA Binding Sites Reveals the Argonaute Regulatory Landscape of the C. elegans Germline.

Shen, En-Zhi; Chen, Hao; Ozturk, Ahmet R; Tu, Shikui; Shirayama, Masaki; Tang, Wen; Ding, Yue-He; Dai, Si-Yuan; Weng, Zhiping; Mello, Craig C.

Afiliação

Shen EZ; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Chen H; Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA; Bioinformatics Program, Boston University, Boston, MA 02215, USA.
Ozturk AR; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Tu S; Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA; Department of Computer Science and Engineering, and CMaCH center, Shanghai Jiao Tong University, Shanghai, China.
Shirayama M; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA; Howard Hughes Medical Institute.
Tang W; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Ding YH; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Dai SY; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Weng Z; Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Mello CC; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA; Howard Hughes Medical Institute. Electronic address: Craig.Mello@umassmed.edu.

Cell ; 172(5): 937-951.e18, 2018 02 22.

Article em En | MEDLINE | ID: mdl-29456082

Assuntos

Proteínas de Caenorhabditis elegans/metabolismo; Caenorhabditis elegans/metabolismo; Células Germinativas/metabolismo; RNA Interferente Pequeno/metabolismo; Sequência de Aminoácidos; Animais; Pareamento de Bases; Sequência de Bases; Sítios de Ligação; Proteínas de Caenorhabditis elegans/química; Quimera/metabolismo; Inativação Gênica; RNA Mensageiro/genética; RNA Mensageiro/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Caenorhabditis elegans / Proteínas de Caenorhabditis elegans / RNA Interferente Pequeno / Células Germinativas Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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