LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during late mitosis.

Hong, Ye; Sonneville, Remi; Wang, Bin; Scheidt, Viktor; Meier, Bettina; Woglar, Alexander; Demetriou, Sarah; Labib, Karim; Jantsch, Verena; Gartner, Anton

Hong, Ye; Sonneville, Remi; Wang, Bin; Scheidt, Viktor; Meier, Bettina; Woglar, Alexander; Demetriou, Sarah; Labib, Karim; Jantsch, Verena; Gartner, Anton.

Afiliação

Hong Y; Centre for Gene Regulation and Expression, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK.
Sonneville R; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK.
Wang B; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK.
Scheidt V; Centre for Gene Regulation and Expression, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK.
Meier B; Centre for Gene Regulation and Expression, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK.
Woglar A; Centre for Gene Regulation and Expression, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK.
Demetriou S; Department of Chromosome Biology, Max F. Perutz Laboratories, Vienna Biocenter, University of Vienna, Vienna, A-1030, Austria.
Labib K; Departments of Developmental Biology and Genetics, Stanford University School of Medicine, Stanford, CA 94305-5329, USA.
Jantsch V; Centre for Gene Regulation and Expression, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK.
Gartner A; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK.

Nat Commun ; 9(1): 728, 2018 02 20.

Article em En | MEDLINE | ID: mdl-29463814

Assuntos

Proteínas de Caenorhabditis elegans/metabolismo; Caenorhabditis elegans/enzimologia; Cromatina/metabolismo; Endodesoxirribonucleases/metabolismo; Mitose; Animais; Caenorhabditis elegans/embriologia; Caenorhabditis elegans/genética; Caenorhabditis elegans/metabolismo; Proteínas de Caenorhabditis elegans/genética; Cromatina/genética; Citocinese; DNA/genética; DNA/metabolismo; Replicação do DNA; Endodesoxirribonucleases/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromatina / Caenorhabditis elegans / Proteínas de Caenorhabditis elegans / Endodesoxirribonucleases / Mitose Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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