In vivo thrombin generation and subsequent APC formation are increased in factor V Leiden carriers.

Rühl, Heiko; Winterhagen, Franziska Isabelle; Berens, Christina; Müller, Jens; Oldenburg, Johannes; Pötzsch, Bernd

Rühl, Heiko; Winterhagen, Franziska Isabelle; Berens, Christina; Müller, Jens; Oldenburg, Johannes; Pötzsch, Bernd.

Afiliação

Rühl H; Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany.
Winterhagen FI; Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany.
Berens C; Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany.
Müller J; Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany.
Oldenburg J; Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany.
Pötzsch B; Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany.

Blood ; 131(13): 1489-1492, 2018 03 29.

Article em En | MEDLINE | ID: mdl-29467181

Assuntos

Fator V/metabolismo; Proteína C/metabolismo; Trombina/metabolismo; Tromboembolia Venosa/sangue; Adolescente; Adulto; Fator V/genética; Feminino; Humanos; Masculino; Pessoa de Meia-Idade; Proteína C/genética; Trombina/genética; Tromboembolia Venosa/genética; Tromboembolia Venosa/patologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator V / Proteína C / Trombina / Tromboembolia Venosa Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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