Evaluation of Epithelial Lining Fluid Concentration of Amikacin in Critically Ill Patients With Ventilator-Associated Pneumonia.

Najmeddin, Farhad; Shahrami, Bita; Azadbakht, Sayna; Dianatkhah, Mehrnoush; Rouini, Mohammad Reza; Najafi, Atabak; Ahmadi, Arezoo; Sharifnia, Hamidreza; Mojtahedzadeh, Mojtaba

Najmeddin, Farhad; Shahrami, Bita; Azadbakht, Sayna; Dianatkhah, Mehrnoush; Rouini, Mohammad Reza; Najafi, Atabak; Ahmadi, Arezoo; Sharifnia, Hamidreza; Mojtahedzadeh, Mojtaba.

Afiliação

Najmeddin F; Department of Clinical Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Shahrami B; Department of Clinical Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Azadbakht S; School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Dianatkhah M; Department of Clinical Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Rouini MR; Department of Pharmaceutics, Tehran University of Medical Sciences, Tehran, Iran.
Najafi A; Department of Anesthesiology and Critical Care, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Ahmadi A; Department of Anesthesiology and Critical Care, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Sharifnia H; Department of Anesthesiology and Critical Care, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Mojtahedzadeh M; Department of Clinical Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

J Intensive Care Med ; 35(4): 400-404, 2020 Apr.

Article em En | MEDLINE | ID: mdl-29471721

Assuntos

Amicacina/administração & dosagem; Antibacterianos/administração & dosagem; Líquido da Lavagem Broncoalveolar/química; Pneumonia Associada à Ventilação Mecânica/tratamento farmacológico; Pneumonia Associada à Ventilação Mecânica/metabolismo; Adulto; Idoso; Amicacina/metabolismo; Antibacterianos/metabolismo; Estado Terminal/terapia; Feminino; Humanos; Pulmão/efeitos dos fármacos; Masculino; Pessoa de Meia-Idade; Projetos Piloto; Pneumonia Associada à Ventilação Mecânica/etiologia; Alvéolos Pulmonares/efeitos dos fármacos; Mucosa Respiratória/efeitos dos fármacos

Palavras-chave

alveolar lining fluid (ALF); amikacin; critical illness; epithelial lining fluid (ELF); lung tissue penetration; ventilator-associated pneumonia (VAP)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Líquido da Lavagem Broncoalveolar / Amicacina / Pneumonia Associada à Ventilação Mecânica / Antibacterianos Tipo de estudo: Etiology_studies / Evaluation_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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