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Mass Spectrometry-Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers.
Mundt, Filip; Rajput, Sandeep; Li, Shunqiang; Ruggles, Kelly V; Mooradian, Arshag D; Mertins, Philipp; Gillette, Michael A; Krug, Karsten; Guo, Zhanfang; Hoog, Jeremy; Erdmann-Gilmore, Petra; Primeau, Tina; Huang, Shixia; Edwards, Dean P; Wang, Xiaowei; Wang, Xuya; Kawaler, Emily; Mani, D R; Clauser, Karl R; Gao, Feng; Luo, Jingqin; Davies, Sherri R; Johnson, Gary L; Huang, Kuan-Lin; Yoon, Christopher J; Ding, Li; Fenyö, David; Ellis, Matthew J; Townsend, R Reid; Held, Jason M; Carr, Steven A; Ma, Cynthia X.
Afiliação
  • Mundt F; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
  • Rajput S; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
  • Li S; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
  • Ruggles KV; Department of Medicine, New York University Langone Health, New York, New York.
  • Mooradian AD; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
  • Mertins P; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
  • Gillette MA; Proteomics Platform, Max Delbrück Center for Molecular Medicine in the Helmholtz Society, Berlin, Germany and Berlin Institute of Health, Berlin, Germany.
  • Krug K; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
  • Guo Z; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, Massachusetts.
  • Hoog J; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
  • Erdmann-Gilmore P; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
  • Primeau T; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
  • Huang S; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
  • Edwards DP; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
  • Wang X; Dan L. Duncan Cancer Center and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.
  • Wang X; Dan L. Duncan Cancer Center and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.
  • Kawaler E; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri.
  • Mani DR; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, New York University Langone Health, New York, New York.
  • Clauser KR; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, New York University Langone Health, New York, New York.
  • Gao F; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
  • Luo J; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
  • Davies SR; Division of Public Health Science, Siteman Cancer Center Biostatistics Core, Washington University School of Medicine, St. Louis, Missouri.
  • Johnson GL; Division of Public Health Science, Siteman Cancer Center Biostatistics Core, Washington University School of Medicine, St. Louis, Missouri.
  • Huang KL; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
  • Yoon CJ; Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
  • Ding L; Department of Medicine, McDonnell Genome Institute, Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri.
  • Fenyö D; Department of Medicine, McDonnell Genome Institute, Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri.
  • Ellis MJ; Department of Medicine, McDonnell Genome Institute, Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri.
  • Townsend RR; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, New York University Langone Health, New York, New York.
  • Held JM; Lester and Sue Smith Breast Center, Dan L. Duncan Comprehensive Cancer Center and Departments of Medicine and Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.
  • Carr SA; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
  • Ma CX; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Cancer Res ; 78(10): 2732-2746, 2018 05 15.
Article em En | MEDLINE | ID: mdl-29472518
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Morfolinas / MAP Quinase Quinase 4 / Classe I de Fosfatidilinositol 3-Quinases / Neoplasias de Mama Triplo Negativas / Quinases Relacionadas a NIMA / Aminopiridinas / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Morfolinas / MAP Quinase Quinase 4 / Classe I de Fosfatidilinositol 3-Quinases / Neoplasias de Mama Triplo Negativas / Quinases Relacionadas a NIMA / Aminopiridinas / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article