Bilateral activation of STAT3 by phosphorylation at the tyrosine-705 (Y705) and serine-727 (S727) positions and its nuclear translocation in primary sensory neurons following unilateral sciatic nerve injury.

Dubový, Petr; Hradilová-Svízenská, Ivana; Klusáková, Ilona; Kokosová, Viktoria; Brázda, Václav; Joukal, Marek

Dubový, Petr; Hradilová-Svízenská, Ivana; Klusáková, Ilona; Kokosová, Viktoria; Brázda, Václav; Joukal, Marek.

Afiliação

Dubový P; Department of Anatomy, Cellular and Molecular Research Group, Faculty of Medicine, Masaryk University, Kamenice 3, Brno, 62500, Czech Republic. pdubovy@med.muni.cz.
Hradilová-Svízenská I; Department of Anatomy, Cellular and Molecular Research Group, Faculty of Medicine, Masaryk University, Kamenice 3, Brno, 62500, Czech Republic.
Klusáková I; Department of Anatomy, Cellular and Molecular Research Group, Faculty of Medicine, Masaryk University, Kamenice 3, Brno, 62500, Czech Republic.
Kokosová V; Department of Anatomy, Cellular and Molecular Research Group, Faculty of Medicine, Masaryk University, Kamenice 3, Brno, 62500, Czech Republic.
Brázda V; Department of Anatomy, Cellular and Molecular Research Group, Faculty of Medicine, Masaryk University, Kamenice 3, Brno, 62500, Czech Republic.
Joukal M; Department of Anatomy, Cellular and Molecular Research Group, Faculty of Medicine, Masaryk University, Kamenice 3, Brno, 62500, Czech Republic.

Histochem Cell Biol ; 150(1): 37-47, 2018 Jul.

Article em En | MEDLINE | ID: mdl-29488000

Assuntos

Núcleo Celular/metabolismo; Fosfosserina/metabolismo; Fosfotirosina/metabolismo; Fator de Transcrição STAT3/química; Fator de Transcrição STAT3/metabolismo; Neuropatia Ciática/metabolismo; Células Receptoras Sensoriais/metabolismo; Transporte Ativo do Núcleo Celular; Animais; Gânglios Espinais/metabolismo; Gânglios Espinais/patologia; Masculino; Fosforilação; Ratos; Ratos Wistar; Neuropatia Ciática/patologia; Células Receptoras Sensoriais/patologia

Palavras-chave

Dorsal root ganglia; Neuroinflammation; Peripheral nerve injury; Systemic reaction

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfosserina / Células Receptoras Sensoriais / Núcleo Celular / Fosfotirosina / Neuropatia Ciática / Fator de Transcrição STAT3 Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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