Development and optimization of a tumor targeting system based on microbial synthesized PHA biopolymers and PhaP mediated functional modification.

Fan, Fan; Wang, Leilei; Ouyang, Zhenlin; Wen, Yurong; Lu, Xiaoyun

Fan, Fan; Wang, Leilei; Ouyang, Zhenlin; Wen, Yurong; Lu, Xiaoyun.

Afiliação

Fan F; Department of Biological Science and Bioengineering, Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, Shaanxi, People's Republic of China.
Wang L; Department of Biological Science and Bioengineering, Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, Shaanxi, People's Republic of China.
Ouyang Z; Department of Biological Science and Bioengineering, Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, Shaanxi, People's Republic of China.
Wen Y; Department of Biological Science and Bioengineering, Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, Shaanxi, People's Republic of China.
Lu X; Department of Biological Science and Bioengineering, Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, Shaanxi, People's Republic of China. luxy05@mail.xjtu.edu.cn.

Appl Microbiol Biotechnol ; 102(7): 3229-3241, 2018 Apr.

Article em En | MEDLINE | ID: mdl-29497797

Assuntos

Proteínas de Bactérias/metabolismo; Biopolímeros/metabolismo; Proteínas de Ligação a DNA/metabolismo; Sistemas de Liberação de Medicamentos/métodos; Nanopartículas/metabolismo; Poli-Hidroxialcanoatos/metabolismo; Animais; Biopolímeros/biossíntese; Biopolímeros/química; Portadores de Fármacos/química; Portadores de Fármacos/metabolismo; Células HCT116; Humanos; Interações Hidrofóbicas e Hidrofílicas; Masculino; Camundongos Endogâmicos BALB C; Nanopartículas/química; Poli-Hidroxialcanoatos/química

Palavras-chave

Nanoparticles; PHA; PhaP; Residual emulsifiers; Tumor targeting

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Biopolímeros / Sistemas de Liberação de Medicamentos / Proteínas de Ligação a DNA / Nanopartículas / Poli-Hidroxialcanoatos Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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