The cell surface phenotype of human dendritic cells.
Semin Cell Dev Biol
; 86: 3-14, 2019 02.
Article
em En
| MEDLINE
| ID: mdl-29499385
ABSTRACT
Dendritic cells (DC) are bone marrow derived leucocytes that are part of the mononuclear phagocytic system. These are surveillance cells found in all tissues and, as specialised antigen presenting cells, direct immune responses. Membrane molecules on the DC surface form a landscape that defines them as leucocytes and part of the mononuclear phagocytic system, interacts with their environment and directs interactions with other cells. This review describes the DC surface landscape, reflects on the different molecules confirmed to be on their surface and how they provide the basis for manipulation and translation of the potent functions of these cells into new diagnostics and immune therapies for the clinic.
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Base de dados:
MEDLINE
Assunto principal:
Fenótipo
/
Células Dendríticas
Limite:
Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article