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Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets.
Trofimov, Valentin; Kicka, Sébastien; Mucaria, Sabrina; Hanna, Nabil; Ramon-Olayo, Fernando; Del Peral, Laura Vela-Gonzalez; Lelièvre, Joël; Ballell, Lluís; Scapozza, Leonardo; Besra, Gurdyal S; Cox, Jonathan A G; Soldati, Thierry.
Afiliação
  • Trofimov V; Department of Biochemistry, Faculty of Science, University of Geneva, Geneva, Switzerland.
  • Kicka S; Institut Pasteur de Lille, Lille, France.
  • Mucaria S; Department of Biochemistry, Faculty of Science, University of Geneva, Geneva, Switzerland.
  • Hanna N; Pharmaceutical Biochemistry/Chemistry, School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.
  • Ramon-Olayo F; Department of Biochemistry, Faculty of Science, University of Geneva, Geneva, Switzerland.
  • Del Peral LV; GSK, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Lelièvre J; GSK, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Ballell L; GSK, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Scapozza L; GSK, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Besra GS; Pharmaceutical Biochemistry/Chemistry, School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.
  • Cox JAG; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, UK.
  • Soldati T; School of Life & Health Sciences, Aston University, Birmingham, UK. j.a.g.cox@aston.ac.uk.
Sci Rep ; 8(1): 3939, 2018 03 02.
Article em En | MEDLINE | ID: mdl-29500372
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mycobacterium marinum / Acanthamoeba castellanii / Dictyostelium / Descoberta de Drogas / Antituberculosos Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mycobacterium marinum / Acanthamoeba castellanii / Dictyostelium / Descoberta de Drogas / Antituberculosos Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article