The Immunogenicity of a Proline-Substituted Altered Peptide Ligand toward the Cancer-Associated TEIPP Neoepitope Trh4 Is Unrelated to Complex Stability.

Hafstrand, Ida; Doorduijn, Elien M; Sun, Renhua; Talyzina, Anna; Sluijter, Marjolein; Pellegrino, Sara; Sandalova, Tatyana; Duru, Adil Doganay; van Hall, Thorbald; Achour, Adnane

Hafstrand, Ida; Doorduijn, Elien M; Sun, Renhua; Talyzina, Anna; Sluijter, Marjolein; Pellegrino, Sara; Sandalova, Tatyana; Duru, Adil Doganay; van Hall, Thorbald; Achour, Adnane.

Afiliação

Hafstrand I; Science for Life Laboratory, Department of Medicine Solna, Karolinska Institutet, 17165 Stockholm, Sweden.
Doorduijn EM; Department of Infectious Diseases, Karolinska University Hospital, Solna, 17176 Stockholm, Sweden.
Sun R; Medical Oncology, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands.
Talyzina A; Science for Life Laboratory, Department of Medicine Solna, Karolinska Institutet, 17165 Stockholm, Sweden.
Sluijter M; Department of Infectious Diseases, Karolinska University Hospital, Solna, 17176 Stockholm, Sweden.
Pellegrino S; Science for Life Laboratory, Department of Medicine Solna, Karolinska Institutet, 17165 Stockholm, Sweden.
Sandalova T; Department of Infectious Diseases, Karolinska University Hospital, Solna, 17176 Stockholm, Sweden.
Duru AD; Medical Oncology, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands.
van Hall T; Department of Pharmaceutical Science, General and Organic Chemistry Section, University of Milan, 20133 Milan, Italy.
Achour A; Science for Life Laboratory, Department of Medicine Solna, Karolinska Institutet, 17165 Stockholm, Sweden.

J Immunol ; 200(8): 2860-2868, 2018 04 15.

Article em En | MEDLINE | ID: mdl-29507106

Assuntos

Antígenos de Neoplasias/imunologia; Vacinas Anticâncer/química; Vacinas Anticâncer/imunologia; Proteínas de Membrana/química; Proteínas de Membrana/imunologia; Animais; Antígenos de Neoplasias/química; Epitopos de Linfócito T/imunologia; Antígeno de Histocompatibilidade H-2D/química; Antígeno de Histocompatibilidade H-2D/imunologia; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Peptídeos; Prolina; Estabilidade Proteica

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vacinas Anticâncer / Proteínas de Membrana / Antígenos de Neoplasias Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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