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Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice.
Mitchell, Sarah J; Bernier, Michel; Aon, Miguel A; Cortassa, Sonia; Kim, Eun Young; Fang, Evandro F; Palacios, Hector H; Ali, Ahmed; Navas-Enamorado, Ignacio; Di Francesco, Andrea; Kaiser, Tamzin A; Waltz, Tyler B; Zhang, Ning; Ellis, James L; Elliott, Peter J; Frederick, David W; Bohr, Vilhelm A; Schmidt, Mark S; Brenner, Charles; Sinclair, David A; Sauve, Anthony A; Baur, Joseph A; de Cabo, Rafael.
Afiliação
  • Mitchell SJ; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Bernier M; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Aon MA; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA; Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Cortassa S; Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Kim EY; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA; Functional Genomics Research Center, KRIBB, Daejeon 305-806, Republic of Korea.
  • Fang EF; Laboratory of Molecular Gerontology, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Palacios HH; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Ali A; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Navas-Enamorado I; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Di Francesco A; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Kaiser TA; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Waltz TB; Laboratory of Molecular Gerontology, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Zhang N; Department of Pharmacology, Weill Cornell Medicine, Cornell University, New York, NY 10065, USA.
  • Ellis JL; Sirtris, a GSK Company, 200 Technology Square, Cambridge, MA 02139, USA.
  • Elliott PJ; Sirtris, a GSK Company, 200 Technology Square, Cambridge, MA 02139, USA.
  • Frederick DW; Department of Physiology, Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Bohr VA; Laboratory of Molecular Gerontology, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Schmidt MS; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
  • Brenner C; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
  • Sinclair DA; Glenn Labs for the Biological Mechanisms of Aging, Harvard Medical School, Boston, MA 02115, USA.
  • Sauve AA; Department of Pharmacology, Weill Cornell Medicine, Cornell University, New York, NY 10065, USA.
  • Baur JA; Department of Physiology, Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • de Cabo R; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA. Electronic address: decabora@grc.nia.nih.gov.
Cell Metab ; 27(3): 667-676.e4, 2018 03 06.
Article em En | MEDLINE | ID: mdl-29514072

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Niacinamida / Suplementos Nutricionais / Envelhecimento Saudável / Fígado / NAD Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Niacinamida / Suplementos Nutricionais / Envelhecimento Saudável / Fígado / NAD Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article