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Design, synthesis, nuclear localization, and biological activity of a fluorescent duocarmycin analog, HxTfA.
Kiakos, Konstantinos; Englinger, Bernhard; Yanow, Stephanie K; Wernitznig, Debora; Jakupec, Michael A; Berger, Walter; Keppler, Bernhard K; Hartley, John A; Lee, Moses; Patil, Pravin C.
Afiliação
  • Kiakos K; Cancer Research UK Drug-DNA Interactions Research Group, UCL Cancer Institute, London WC1E 6BT, United Kingdom; Institute of Inorganic Chemistry, University of Vienna, Waehringer Str. 42, 1090 Vienna, Austria; Research Cluster "Translational Cancer Therapy Research", University of Vienna, Waehringer
  • Englinger B; Institute of Cancer Research and Comprehensive Cancer Center, Department of Medicine I, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna, Austria.
  • Yanow SK; School of Public Health, University of Alberta, Edmonton, Canada.
  • Wernitznig D; Institute of Inorganic Chemistry, University of Vienna, Waehringer Str. 42, 1090 Vienna, Austria; Research Cluster "Translational Cancer Therapy Research", University of Vienna, Waehringer Str. 42, 1090 Vienna, Austria.
  • Jakupec MA; Institute of Inorganic Chemistry, University of Vienna, Waehringer Str. 42, 1090 Vienna, Austria; Research Cluster "Translational Cancer Therapy Research", University of Vienna, Waehringer Str. 42, 1090 Vienna, Austria.
  • Berger W; Research Cluster "Translational Cancer Therapy Research", University of Vienna, Waehringer Str. 42, 1090 Vienna, Austria; Institute of Cancer Research and Comprehensive Cancer Center, Department of Medicine I, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna, Austria.
  • Keppler BK; Institute of Inorganic Chemistry, University of Vienna, Waehringer Str. 42, 1090 Vienna, Austria; Research Cluster "Translational Cancer Therapy Research", University of Vienna, Waehringer Str. 42, 1090 Vienna, Austria.
  • Hartley JA; Cancer Research UK Drug-DNA Interactions Research Group, UCL Cancer Institute, London WC1E 6BT, United Kingdom.
  • Lee M; Department of Chemistry, Hope College, Holland, MI 49423, United States.
  • Patil PC; Department of Chemistry, Hope College, Holland, MI 49423, United States.
Bioorg Med Chem Lett ; 28(8): 1342-1347, 2018 05 01.
Article em En | MEDLINE | ID: mdl-29548574
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzimidazóis / DNA / Núcleo Celular / Corantes Fluorescentes / Indóis / Antimaláricos Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzimidazóis / DNA / Núcleo Celular / Corantes Fluorescentes / Indóis / Antimaláricos Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article