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Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial.
Lai, Zhi-Wei; Kelly, Ryan; Winans, Thomas; Marchena, Ivan; Shadakshari, Ashwini; Yu, Julie; Dawood, Maha; Garcia, Ricardo; Tily, Hajra; Francis, Lisa; Faraone, Stephen V; Phillips, Paul E; Perl, Andras.
Afiliação
  • Lai ZW; Division of Rheumatology, State University of New York Upstate Medical University, Syracuse, NY, USA; Department of Medicine, State University of New York Upstate Medical University, Syracuse, NY, USA.
  • Kelly R; Division of Rheumatology, State University of New York Upstate Medical University, Syracuse, NY, USA; Department of Medicine, State University of New York Upstate Medical University, Syracuse, NY, USA.
  • Winans T; Division of Rheumatology, State University of New York Upstate Medical University, Syracuse, NY, USA; Department of Medicine, State University of New York Upstate Medical University, Syracuse, NY, USA.
  • Marchena I; Division of Rheumatology, State University of New York Upstate Medical University, Syracuse, NY, USA; Department of Medicine, State University of New York Upstate Medical University, Syracuse, NY, USA.
  • Shadakshari A; Division of Rheumatology, State University of New York Upstate Medical University, Syracuse, NY, USA; Department of Medicine, State University of New York Upstate Medical University, Syracuse, NY, USA.
  • Yu J; Division of Rheumatology, State University of New York Upstate Medical University, Syracuse, NY, USA; Department of Medicine, State University of New York Upstate Medical University, Syracuse, NY, USA.
  • Dawood M; Division of Rheumatology, State University of New York Upstate Medical University, Syracuse, NY, USA; Department of Medicine, State University of New York Upstate Medical University, Syracuse, NY, USA.
  • Garcia R; Division of Rheumatology, State University of New York Upstate Medical University, Syracuse, NY, USA; Department of Medicine, State University of New York Upstate Medical University, Syracuse, NY, USA.
  • Tily H; Division of Rheumatology, State University of New York Upstate Medical University, Syracuse, NY, USA; Department of Medicine, State University of New York Upstate Medical University, Syracuse, NY, USA.
  • Francis L; Division of Rheumatology, State University of New York Upstate Medical University, Syracuse, NY, USA; Department of Medicine, State University of New York Upstate Medical University, Syracuse, NY, USA.
  • Faraone SV; Department of Psychiatry, State University of New York Upstate Medical University, Syracuse, NY, USA.
  • Phillips PE; Division of Rheumatology, State University of New York Upstate Medical University, Syracuse, NY, USA; Department of Medicine, State University of New York Upstate Medical University, Syracuse, NY, USA.
  • Perl A; Division of Rheumatology, State University of New York Upstate Medical University, Syracuse, NY, USA; Department of Medicine, State University of New York Upstate Medical University, Syracuse, NY, USA; Department of Microbiology and Immunology, State University of New York Upstate Medical University
Lancet ; 391(10126): 1186-1196, 2018 03 24.
Article em En | MEDLINE | ID: mdl-29551338

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sirolimo / Imunossupressores / Lúpus Eritematoso Sistêmico Tipo de estudo: Clinical_trials / Observational_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sirolimo / Imunossupressores / Lúpus Eritematoso Sistêmico Tipo de estudo: Clinical_trials / Observational_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article