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The antipsychotics sulpiride induces fatty liver in rats via phosphorylation of insulin receptor substrate-1 at Serine 307-mediated adipose tissue insulin resistance.
Zhou, Xia; Ren, Liying; Yu, Zhiling; Huang, Xiaoqian; Li, Yuhao; Wang, Chunxia.
Afiliação
  • Zhou X; Department of Pharmacy, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
  • Ren L; Department of Pharmacy, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
  • Yu Z; School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
  • Huang X; Department of Pharmacy, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
  • Li Y; Endocrinology and Metabolism Group, Sydney Institute of Health Sciences/Sydney Institute of Traditional Chinese Medicine, NSW 2000, Australia.
  • Wang C; Department of Pharmacy, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China. Electronic address: wangcx@smu.edu.cn.
Toxicol Appl Pharmacol ; 345: 66-74, 2018 04 15.
Article em En | MEDLINE | ID: mdl-29551354
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulpirida / Antipsicóticos / Resistência à Insulina / Tecido Adiposo / Proteínas Substratos do Receptor de Insulina / Fígado Gorduroso Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulpirida / Antipsicóticos / Resistência à Insulina / Tecido Adiposo / Proteínas Substratos do Receptor de Insulina / Fígado Gorduroso Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article