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The tyrosine-kinase inhibitor sunitinib targets vascular endothelial (VE)-cadherin: a marker of response to antitumoural treatment in metastatic renal cell carcinoma.
Polena, Helena; Creuzet, Julie; Dufies, Maeva; Sidibé, Adama; Khalil-Mgharbel, Abir; Salomon, Aude; Deroux, Alban; Quesada, Jean-Louis; Roelants, Caroline; Filhol, Odile; Cochet, Claude; Blanc, Ellen; Ferlay-Segura, Céline; Borchiellini, Delphine; Ferrero, Jean-Marc; Escudier, Bernard; Négrier, Sylvie; Pages, Gilles; Vilgrain, Isabelle.
Afiliação
  • Polena H; Univ-Grenoble Alpes, INSERM, CNRS, BIG-BCI Biology of Cancer and Infection, Grenoble, F- 38054, France.
  • Creuzet J; Univ-Grenoble Alpes, INSERM, CNRS, BIG-BCI Biology of Cancer and Infection, Grenoble, F- 38054, France.
  • Dufies M; Biomedical Department, Centre Scientifique de Monaco, Monaco, Monaco.
  • Sidibé A; Univ-Grenoble Alpes, INSERM, CNRS, BIG-BCI Biology of Cancer and Infection, Grenoble, F- 38054, France.
  • Khalil-Mgharbel A; Univ-Grenoble Alpes, INSERM, CNRS, BIG-BCI Biology of Cancer and Infection, Grenoble, F- 38054, France.
  • Salomon A; Univ-Grenoble Alpes, INSERM, CNRS, BIG-BCI Biology of Cancer and Infection, Grenoble, F- 38054, France.
  • Deroux A; Grenoble University Hospital, Division of Internal Medicine, Grenoble, F-38043, France.
  • Quesada JL; INSERM, Unité 003, Clinical Investigation Center, Grenoble University Hospital, Grenoble, F-38043, France.
  • Roelants C; Univ-Grenoble Alpes, INSERM, CNRS, BIG-BCI Biology of Cancer and Infection, Grenoble, F- 38054, France.
  • Filhol O; Univ-Grenoble Alpes, INSERM, CNRS, BIG-BCI Biology of Cancer and Infection, Grenoble, F- 38054, France.
  • Cochet C; Univ-Grenoble Alpes, INSERM, CNRS, BIG-BCI Biology of Cancer and Infection, Grenoble, F- 38054, France.
  • Blanc E; Unicancer, Centre de Lutte contre Le Cancer Léon Bérard, Lyon, F-69008, France.
  • Ferlay-Segura C; Unicancer, Centre de Lutte contre Le Cancer Léon Bérard, Lyon, F-69008, France.
  • Borchiellini D; Department of Clinical Research, Innovation and Statistics, Centre Antoine Lacassagne, Nice, F-06000, France.
  • Ferrero JM; Department of Clinical Research, Innovation and Statistics, Centre Antoine Lacassagne, Nice, F-06000, France.
  • Escudier B; Gustave Roussy Cancer Campus, Grand Paris, Villejuif, F-94800, France.
  • Négrier S; Unicancer, Centre de Lutte contre Le Cancer Léon Bérard, Lyon, F-69008, France.
  • Pages G; University of Nice Sophia Antipolis, Institute for Research on Cancer and Aging of Nice, CNRS UMR 7284, INSERM U1081, Centre Antoine Lacassagne, Nice, F-06107, France.
  • Vilgrain I; Univ-Grenoble Alpes, INSERM, CNRS, BIG-BCI Biology of Cancer and Infection, Grenoble, F- 38054, France. ivilgrain@cea.fr.
Br J Cancer ; 118(9): 1179-1188, 2018 05.
Article em En | MEDLINE | ID: mdl-29563634
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Endotélio Vascular / Carcinoma de Células Renais / Caderinas / Biomarcadores Farmacológicos / Sunitinibe / Neoplasias Renais / Antineoplásicos Tipo de estudo: Observational_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Endotélio Vascular / Carcinoma de Células Renais / Caderinas / Biomarcadores Farmacológicos / Sunitinibe / Neoplasias Renais / Antineoplásicos Tipo de estudo: Observational_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article