Discovery, gene modification, and optimization of fermentation of an enduracidin-producing strain.
J Asian Nat Prod Res
; 20(7): 633-648, 2018 Jul.
Article
em En
| MEDLINE
| ID: mdl-29589483
ABSTRACT
Enduracidin significantly inhibits Gram-positive bacteria and had been widely used in many fields. However, as the poor technology for production of enduracidin and its scarcity, identification of novel strategies for production of enduracidin is important. Our group developed two methods to improve the yield of the production of enduracidin. The yield of enduracidin was increased by three- to fivefold. The highest yields of enduracidin A and enduracidin B achieved were 63.7 and 82.13 mg/ml. Thus, our results might provide a new reference method for the industrial production of enduracidin.
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Base de dados:
MEDLINE
Assunto principal:
Peptídeos Cíclicos
/
Antibacterianos
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article